产品货号:
Z10362
中文名称:
ACK1/TNK2抗体
英文名称:
Anti-ACK1/TNK2 Antibody
产品规格:
100μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-ACK1/TNK2 Antibody |
指标别名 | ACK;ACK 1;ACK1;Activated CDC42 kinase 1;p21cdc42Hs;TNK2 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB,ELISA |
基因名称 | TNK2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | Synthesized peptide derived from human ACK around the non-phosphorylation site of Y284. |
计算分子量 | 115KD |
成分 | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
纯化方式 | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | -20℃可保存1年,短期保存或频繁使用请置于4℃,可保存一个月,避免反复冻融。 |
背景资料 | Activated CDC42 kinase 1,also known as ACK1,is an enzyme that in humans is encoded by the TNK2 gene.This gene encodes a tyrosine kinase that binds Cdc42Hs in its GTP-bound form and inhibits both the intrinsic and GTPase-activating protein (GAP)-stimulated GTPase activity of Cdc42Hs.This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain.The protein may be involved in a regulatory mechanism that sustains the GTP-bound active form of Cdc42Hs and which is directly linked to a tyrosine phosphorylation signal transduction pathway.Several alternatively spliced transcript variants have been identified from this gene,but the full-length nature of only two transcript variants has been determined. |
Uniprot ID | Q07912 |
基因名全称 | Activated CDC42 kinase 1 |
蛋白名全称 | Activated CDC42 kinase 1 |
推荐稀释比 | WB 1:500~1:2000 ELISA 1:10000 |
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